Mear ynformaasje ― Frysk

Pigmented purpuric dermatoses (PPD) binne in groep hûdomstannichheden markearre troch lytse gebieten fan bloed ûnder de hûd fanwegen kapillêre ûntstekking. PPD begjint typysk as reade oant pearse flekken dy't letter gouden-brún wurde as de hemosiderin opnij opnommen wurdt.
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.

Schamberg disease is it meast foarkommende type pigmented purpuric dermatoses (PPDs) , dy't chronike hûdsomstannichheden binne karakterisearre troch lytse reade of pearse plakken, en ferhege hûdkleur (flekken fan brún, read of giel) . PPD's wurde yndield yn fiif soarten: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura, eczematoid-like purpura of Doucas and Kapetanakis. Schamberg disease (SD) is ek bekend as progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressiva, Schamberg's purpura. It treft benammen manlju en ferskynt typysk op 'e legere skonken, mar kin ek foarkomme op' e dijen, billen, romp of earms.
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.

Ynformaasje oer 113 pasjinten mei PPD waard analysearre, wêrûnder 38 dy't hûdbiopsy ûndergie foar dizze stúdzje. De meast foarkommende klinyske type wie de sykte fan Schamberg (60,5%) . Oare betingsten neist PPD wiene hypertensie (15,8%) , diabetes (10,5%) , en oaren. Medikaasjehistoarjes iepenbiere statins (13. 2%) , beta-blokkers (10. 5%) , en oaren. Mooglike faktoaren keppele oan PPD omfette resinte ynfeksje fan 'e boppeste luchtwegen (5,3%) , langer stean dy't liedt ta hege ortostatyske druk (2,6%) , en ynspannende oefening (2,6%) . Behanneling waard administraasje oan 36 pasjinten (94,7%) - oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.